Two sample MR report
ELP5_T Proliferating against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.0046832 | 0.0754792 | 0.9529298 |
| Weighted median | 7 | -0.0244632 | 0.0085509 | 0.0042245 |
| Inverse variance weighted | 7 | -0.0257443 | 0.0068282 | 0.0001631 |
| Simple mode | 7 | -0.0243702 | 0.0122223 | 0.0932092 |
| Weighted mode | 7 | -0.0242682 | 0.0115936 | 0.0812332 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1712782 | 5 | 0.9993924 |
| Inverse variance weighted | 0.3351283 | 6 | 0.9993081 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0205679 | 0.050812 | 0.7023722 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001788 | 0 | TRUE | 0.2056919 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
